KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGL
All Species:
18.18
Human Site:
Y1249
Identified Species:
36.36
UniProt:
P35573
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35573
NP_000019.2
1532
174764
Y1249
D
E
E
T
G
F
V
Y
G
G
N
R
F
N
C
Chimpanzee
Pan troglodytes
XP_524777
1532
174746
Y1249
D
E
E
T
G
F
V
Y
G
G
N
R
F
N
C
Rhesus Macaque
Macaca mulatta
XP_001106231
1532
174684
Y1249
D
E
E
T
G
F
V
Y
G
G
N
R
F
N
C
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074795
1532
174269
Y1249
D
E
E
T
G
F
V
Y
G
G
N
R
F
N
C
Rat
Rattus norvegicus
NP_001102034
1532
174314
Y1249
D
E
E
T
G
F
V
Y
G
G
N
R
F
N
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512323
1163
131293
D892
F
N
C
G
T
W
M
D
K
M
G
E
S
D
R
Chicken
Gallus gallus
XP_422317
1532
174660
F1249
D
R
E
T
G
F
V
F
G
G
N
R
F
N
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696194
1052
117860
D781
F
N
C
G
T
W
M
D
K
M
G
E
S
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726062
1629
183200
F1345
H
P
E
T
G
F
V
F
G
G
N
N
F
N
C
Honey Bee
Apis mellifera
XP_394961
1549
176545
G1249
P
E
T
G
F
I
F
G
G
N
D
A
N
C
G
Nematode Worm
Caenorhab. elegans
NP_496984
1467
165910
G1190
A
G
V
S
R
T
T
G
F
I
Y
G
G
N
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06625
1536
174953
H1237
D
W
S
T
G
L
I
H
G
G
S
Q
Y
N
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.6
N.A.
N.A.
91.9
92.1
N.A.
67.6
81.7
N.A.
53.3
N.A.
45.2
49.9
44.2
N.A.
Protein Similarity:
100
100
99.2
N.A.
N.A.
96.6
96.4
N.A.
72
91.5
N.A.
61.3
N.A.
61.4
66.6
62
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
0
86.6
N.A.
0
N.A.
73.3
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
20
93.3
N.A.
13.3
N.A.
80
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
17
0
0
0
0
0
0
0
0
0
0
9
67
% C
% Asp:
59
0
0
0
0
0
0
17
0
0
9
0
0
9
0
% D
% Glu:
0
50
59
0
0
0
0
0
0
0
0
17
0
9
0
% E
% Phe:
17
0
0
0
9
59
9
17
9
0
0
0
59
0
0
% F
% Gly:
0
9
0
25
67
0
0
17
75
67
17
9
9
0
9
% G
% His:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
9
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
17
0
0
17
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
0
0
0
9
59
9
9
75
0
% N
% Pro:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
9
0
0
9
0
0
0
0
0
0
50
0
0
25
% R
% Ser:
0
0
9
9
0
0
0
0
0
0
9
0
17
0
0
% S
% Thr:
0
0
9
67
17
9
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
59
0
0
0
0
0
0
0
0
% V
% Trp:
0
9
0
0
0
17
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
0
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _